OncoStrands® Essential Combined (DNA + Fusion) / Essential DNA / Essential Fusion

Specimen Requirements
Clinical usage	Utilizes Next Generation Sequencing (NGS) to identify somatic mutations within 50 targeted genes associated with different tumour types, including lung, colon, skin, urinary bladder, stomach, thyroid and others. This assay simultaneously screens for different types of mutations including DNA hotspots from 45 genes, copy number variations (CNVs) from 14 genes and fusions from 18 genes. NOTE: Essential DNA or Essential Fusion can be ordered individually
Type of sample	Formalin-fixed paraffin-embedded (FFPE) Tissue/Cell Block (preferred) or 10 x 5µm unstained slides of FFPE tissue mounted on uncoated slides + 1 H&E stained slide
Surface Area & Tumour Purity	Minimum surface area of 5 x 5 mm2 per slide. If the tissue area is smaller, please provide additional 5 – 10 5µm unstained slides. At least 10% tumour purity per slide.
Storage & transportation	Please keep at room temperature. Do not freeze, and keep away from direct sunlight.
Turnaround Time (TAT)	2 weeks

Specimen Requirements

Clinical usage

Utilizes Next Generation Sequencing (NGS) to identify somatic mutations within 50 targeted genes associated with different tumour types, including lung, colon, skin, urinary bladder, stomach, thyroid and others. This assay simultaneously screens for different types of mutations including DNA hotspots from 45 genes, copy number variations (CNVs) from 14 genes and fusions from 18 genes.

NOTE: Essential DNA or Essential Fusion can be ordered individually

Type of sample

Formalin-fixed paraffin-embedded (FFPE) Tissue/Cell Block (preferred) or 10 x 5µm unstained slides of FFPE tissue mounted on uncoated slides + 1 H&E stained slide

Surface Area & Tumour Purity

Minimum surface area of 5 x 5 mm2 per slide. If the tissue area is smaller, please provide additional 5 – 10 5µm unstained slides. At least 10% tumour purity per slide.

Storage & transportation

Please keep at room temperature. Do not freeze, and keep away from direct sunlight.

Turnaround Time (TAT)

2 weeks